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Revista Cubana de Hematología, Inmunología y Hemoterapia
versão On-line ISSN 1561-2996
Resumo
ALONSO-MARINO, Olga Lidia e ALONSO-MARINO, Ana Luisa. Acquired hemophilia A. A case report. Rev Cubana Hematol Inmunol Hemoter [online]. 2018, vol.34, n.3, pp. 1-5. ISSN 1561-2996.
Acquired hemophilia A is a rare bleeding disorder characterized by the presence of autoantibodies against circulating factor VIII (FVIII). It has been observed in a heterogeneous group of entities that include, among others, malignant diseases; 32 % associated with urological processes, where prostate cancer has the highest prevalence. We present a patient who was treated at the Oncology Service of the Celestino Hernández Robau University Hospital with the diagnosis of acquired hemophilia A in the course of a prostatic adenocarcinoma. A coagulation study was carried out at the Institute of Hematology and Immunology where the presence of factor VIII inhibitor was confirmed, confirming the diagnosis. Immunosuppressive treatment was given with prednisone 1 mg/kg of weight, with a favorable evolution.
Palavras-chave : acquired hemophilia; autoantibodies; factor VIII.