Introduction:

Scientific evidence associates the use of invasive mechanical ventilation with a higher probability of developing acute kidney injury, but the lack of consensus on this association is not uncommon.

Objective:

To identify the relationship between mechanical ventilation times and the onset and severity of acute kidney injury.

Methods:

Historical cohort carried out, between 2016 and 2018, in an intensive care unit of the Federal District, Brazil. The population consisted of 387 patients, but the sample consisted of 52 patients who required invasive mechanical ventilation for one week and two. The data were recorded with a structured questionnaire composed of identification variables, clinical data, hemodynamic variables and laboratory parameters. Chi-square, Fisher's exact and Mann-Whitney tests were used for the association analysis. Results with P < 0.05 were considered significant.

Results:

Acute kidney injury of different severity degrees predominated in more than half of the patients (55.80%), stage 2 being the most prevalent (approximately 30%). Patients who remained on mechanical ventilation for a week or two showed a decreased risk for acute kidney injury (OR: 0.85, 95% CI: 0.72-0.99, P = 0.038 and OR: 0.77, 95% CI: 0.63-0.94, P = 0.010, respectively).

Conclusion:

Acute kidney injury of different severity degrees was present in patients with invasive mechanical ventilation. However, the time of mechanical ventilation alone was not a determinant of acute kidney injury.

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