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Revista Información Científica
versão On-line ISSN 1028-9933
Resumo
LEON-VIDAL, Maricela de et al. Oxygen markers for predicting COVID-19 - related pneumonia mortality. Rev. inf. cient. [online]. 2022, vol.101, n.6 Epub 16-Dez-2022. ISSN 1028-9933.
Introduction:
The value of oxygen as a prognostic maker of mortality due to COVID-19 pneumonia has not been evaluated at the Hospital General Docente "Dr. Agostinho Neto".
Objective:
To identify the values of oxygenation markers for prognosing mortality caused by COVID-19 pneumonia at the Hospital General Docente "Dr. Agostinho Neto" de Guantánamo, Cuba, throughout period 2020-2021.
Method:
A cohort of 276 patients with COVID-19 pneumonia was studied. Peripheral oxygen saturation (SpO2), arterial oxygen saturation (SaO2), the difference between the oxygen concentration in the alveoli and arterial system (DA-aO2), arterial oxygen pressure ratio (PaO2) and inspired oxygen fraction (FiO2) [PaO2/FiO2] were studied. The association between variables and deceased discharge was determined using the Chi-square technique and the Odds Ratio (OR) calculation.
Results:
The variable with the highest positive predictive value was SpO2 (87.3 %) with a value lower than 90 mmHg at admission. The highest negative predictive value was recorded for the DA-aO2 variable (95.6%), less than 20 mmHg at 48 hours after admission. Attributable risk was higher for PaO2/FiO2 ratio, less than 300 mmHg (0.59), at admission (0.52). Attributable risk percent was higher for the variable DA-aO2 ≥ 20 mmHg at admission (95.8 %) and at 48 hours after admission (95.3 %).
Conclusions:
Abnormal DA-aO2, PaO2/FiO2 ratio, SaO2 and SpO2, at admission and 48 hours after admission, are predictive markers of mortality in patients with COVID-19.
Palavras-chave : COVID-19; oxygen markers; COVID-19 pneumonia; mortality; predictive factors.