Resumo

IZAGUIRRE BORDELOIS, Marioneya  e  SORIANO GONZALEZ, Blanca Inés. Histomorphometric characteristics of homogeneous oral leucoplakia. MEDISAN [online]. 2013, vol.17, n.8, pp. 3035-3041. ISSN 1029-3019.

A descriptive study of 35 patients with homogeneous oral leucoplakia associated with the smoking habit, assisted in the Maxillofacial Surgery Department of "Dr. Juan Bruno Zayas Alfonso" Teaching General Hospital in Santiago de Cuba was carried out from January, 2007 to the same month of 2009, aimed at determining the histomorphometric characteristics of the corresponding biopsies, which could contribute to specify its diagnosis. The histomorphometric examination of the epithelial thickness was carried out as well as that of the nuclear and cytoplasmic diameters; the density of the lymphocytic and vascular infiltrate was also measured in the lamina propria and in the hyperchromatosis. The smallest values of the nuclear diameter were the most frequently found, with a strong association with the cytoplasmic one. These parameters turned out to be the most significant for the diagnosis of the aforementioned disorder.

Palavras-chave : homogeneous oral leucoplakia; histopathology; epithelial dysplasia; pathology; secondary health care.

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