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Medicentro Electrónica
versão On-line ISSN 1029-3043
Resumo
GONZALES ALVAREZ, Yusimí et al. Humoral markers and ultrasonographic study in diabetic patients with liver disease due to fat accumulation. Medicentro Electrónica [online]. 2023, vol.27, n.2 Epub 01-Abr-2023. ISSN 1029-3043.
Introduction:
non-alcoholic fatty liver disease is characterized by an accumulation of fat in the liver in the form of triacylglycerides, absence of inflammation, fibrosis and a consumption of less than 30 degrees of alcohol per day. This condition is associated with diabetes mellitus (especially type 2), and there is a growing increase in the number of hospital visits for this cause.
Objective:
to determine the relationship between humoral markers and ultrasonographic study in diabetic patients with non-alcoholic fatty liver disease.
Methods:
a descriptive and cross-sectional investigation was carried out in the provincial hepatology consultation at "Arnaldo Milián Castro" Clinical and Surgical University Hospital from March 2019 to December 2020. The study universe consisted of 89 patients (older than or equal to 19 years, of both genders); the sample consisted of 66 patients who were selected by non-probabilistic sampling.
Results:
white male patients aged between 40 and 59 years living in urban areas predominated. The predominant degree of steatosis was grade 1 (mild). Humoral markers (glycemia, gamma- glutamyl transpeptidase, albumin and De Ritis ratio) were the most pathologically affected.
Conclusions:
ultrasonographic studies showed a statistically significant association with changes in humoral markers of liver injury, which may alert to a possible unfavorable evolution of this disease.
Palavras-chave : non-alcoholic fatty liver disease; transaminases; diabetes mellitus, type 2; blood glucose; albumins.