Resumo

MUINOS MARTINEZ, Celia  e  RODRIGUEZ CORTINA, Iván. Diabetes insipid us and Zika virus. Rev Cubana Endocrinol [online]. 2020, vol.31, n.3  Epub 20-Jan-2021. ISSN 1561-2953.

Diabetes insipidus is the result of reduced secretion or action of the vasopressin hormone, which is clinically expressed by a polyuria-polydipsia picture. Arboviruses can have a nervous system affinity and Zika has been shown to trigger an autoimmune disorder that attacks nerve cells, which can result in central diabetes insipidus. The reviewed national and international medical literatures does not report previous cases linking diabetes insipidus with Zika virus. It is presented a case about this association: 53-year-old female patient diagnosed with Zika virus infection two weeks before starting symptoms suggestive of diabetes insipidus. The neurotropic potential of the virus, as well as the results in nuclear MRI and the determination of positive anti-ADNdc autoimmunity markers are elements that support the hypothesis that the patient had a possible autoimmune hypophysis, as a post-infection inflammatory response, developing transient central diabetes insipidus.

Palavras-chave : Diabetes insipidus; hypophysis; Zika; arbovirus; vasopressin; autoimmunity.

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