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Revista Cubana de Endocrinología

versão On-line ISSN 1561-2953

Resumo

RODRIGUEZ MARTINEZ, Kenia; MARTINEZ ARAUJO, Adriana; GUTIERREZ ROJAS, Ángela  e  FLORES SANCHEZ, Rosa María. Anti-Müllerian hormone as a marker of ovarian response in patients treated with in vitro fertilization. Rev Cubana Endocrinol [online]. 2021, vol.32, n.1  Epub 01-Abr-2021. ISSN 1561-2953.

Introduction:

Infertility affects to 15% of the couples in childbearing age, and approximately 4-8% of them will need high-tech assisted reproduction techniques. With the participation of women in work life and the subsequent delay of maternity, it is possible the increase of infertility. Anti-Müllerian in women is produced by granular cells. These cells control the recruitment of follicles, their growth and prevent follicles exhaustion; therefore, it represents an important tool in the protocols of ovulation induction.

Objective:

Assess the levels of anti-Müllerian hormone as a marker in the ovarian response in patients treated with in vitro fertilization.

Methods:

It was conducted a descriptive, observational and cross-sectional study in the consultation of Assisted Reproduction in “Hermanos Ameijeiras” Surgical Clinical Hospital, in the period April, 2017 - April, 2019. The sample was formed by 137 women who attended to this consultation. It was used descriptive and inferential statistics.

Results:

Average age of the patients was 33,1 ± 7,4 years old. There was predominance of normal serum concentration of anti-Müllerian hormone in women among 31-35 years old (26,3%), FSH normal level in (39,4%), normal recount of antral follicles (24,1%), good oocyte quality (39,4%), and good embryonic quality (36,5%).

Conclusions:

The serum level of the anti-Müllerian hormone was significantly associated to age, the follicle-stimulating hormone, the recount of antral follicles, and the oocyte and embryonic quality.

Palavras-chave : Ovarian reserve; anti-Müllerian hormone; in vitro fertilization.

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