Resumo

BRITO PEREZ, Katia; CANETE VILLAFRANCA, Roberto; DEL PUERTO HORTA, Myrna  e  GONZALEZ LOPEZ, Maria Elena. Some considerations related to clinical trials. Rev.Med.Electrón. [online]. 2016, vol.38, n.5, pp. 719-724. ISSN 1684-1824.

Clinical trials are controlled and planned experiments involving human  volunteers, used to evaluate the efficacy and safeness of surgical, medical and sanitary interventions, and also to determine the  pharmacologic, pharmacokinetics or pharmacodynamic effects of new therapeutic products, including their adverse reactions study. Considered the paradigm of the epidemiologic research, because they  are the designs that are more similar to an experiment due to the  control of the conditions under study, and because they could establish cause-effect relations, the clinical trials favor decision-making in public health and, beginning from the moment of the  implementation of their results, they contribute to the increase of  the life quality of human beings wherever they live. The priority of  health care decision-makers should be seeing for their correct design, evaluation and following-up by the scientific councils and research  ethic committees, and also for the adequate interpretation of the results and their publication.

Palavras-chave : clinical trial; medical ethic.

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