Resumo

TABOADA LUGO, Noel. Advances in the knowledge of the molecular and cellular bases of congenital heart diseases. Second of two parts: Congenital heart defects. CorSalud [online]. 2019, vol.11, n.4, pp. 307-316.  Epub 01-Dez-2019. ISSN 2078-7170.

Congenital heart defect is the most common birth defect in humans. We conducted a review of the medical literature with the aim of identifying the most recent advances in the knowledge of its molecular and cellular bases. The information obtained was divided into two parts: the first one emphasized on genes and cardiac morphogenesis, and this second part complements the previous one, with special focus on congenital heart defects.

Palavras-chave : Congenital heart defects; Morphogenesis; Single nucleotide polymorphism; Transcription factors; DNA methylation; Signal transduction.

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