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Revista Cubana de Estomatología
versão On-line ISSN 1561-297X
Resumo
IRALA, Eleusys e CASTELLANO DIAZ, Isabel. Risk of Osteoradionecrosis of the Jaws according to Type of Radiotherapy. Rev Cubana Estomatol [online]. 2024, vol.61 Epub 27-Mar-2024. ISSN 1561-297X.
Introduction:
Head and neck cancer is the seventh most common cancer worldwide. Therapeutic options for its management include radiotherapy, which should seek a balance between tumor elimination and preservation of healthy tissue because its application implies the risk of developing osteoradionecrosis of the jaws.
Objective:
To assess whether the risk of developing osteoradionecrosis of the jaws varies according to the type of radiotherapy.
Methods
: Documentary, retrospective design based on the principles of exploratory systematic reviews as established by the PRISMA Extension for Scoping Reviews (PRISMA-ScR) checklist. PubMed, LILACS, ScienceDirect, Tripdatabase and Epistemonikos were searched in English and Spanish.
Results:
In total, 12 studies published between 2016 and 2022 with various research designs were included; the retrospective cohort study had the highest representation. Different radiotherapy options and their protocols were analyzed, including intensity-modulated radiotherapy, intensity-modulated proton therapy, stereotactic body radiotherapy, and three-dimensional radiotherapy. The literature refers that protocols involving lower total doses represent a lower risk of osteoradionecrosis.
Conclusions:
The risk of osteoradionecrosis of the jaws should be attributed, to a greater extent, to the total radiation dose received by the patient and the dose per fraction than to the type of radiotherapy.
Palavras-chave : osteoradionecrosis; head and neck neoplasms radiotherapy; intensity-modulated radiotherapy; proton therapy.