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Revista Cubana de Pediatría
versão On-line ISSN 1561-3119
Resumo
GAROFALO GOMEZ, Nicolás; VARGAS DIAZ, José; NOVOA LOPEZ, Lucía Margarita e DE GRETA BERMUDEZ LINAREZ, Vivian. Atypical evolution of Panayiotopoulos syndrome to continuous spikes and wave’s syndrome during slow sleep. Rev Cubana Pediatr [online]. 2019, vol.91, n.3 Epub 01-Set-2019. ISSN 1561-3119.
Introduction:
Idiopathic focal epilepsies are one of the most frequent epilepsy groups in childhood. Exceptionally, patients with this type of epilepsy have atypical evolutions that constitute a diagnostic and therapeutic challenge.
Objective:
To illustrate the atypical evolution of idiopathic focal epilepsy, type Panayiotopoulos.
Case presentation:
A 13-year-old adolescent who presented his first epileptic seizure at 5 years old, of short duration, while he slept had an eye opening, deviation of the eyes to the left, abundant salivation and vomiting. In three years he had only three seizures. He did not receive treatment with antiepileptic drugs until after the third seizure, which was longer. After starting treatment with carbamazepine, he began to have learning difficulties and marked hyperactivity. A sleep’s interictal electroencephalogram showed continuous spikes and wave’s discharges during the slow sleep. After two years of treatment, the normalization of the sleep electroencephalogram was achieved, with withdrawal of carbamazepine, and progressive introduction of clobazam and magnesium valproate. The patient remained evolutionarily with learning difficulties, with significant improvement in hyperactivity, without recurrence of seizures.
Conclusions:
The case presented is an infrequent example of a patient with idiopathic focal epilepsy with atypical evolution, probably induced by carbamazepine, with clinical-electroencephalographic symptoms during more than two years, with improvement favored by the final treatment used, the natural evolution of the syndrome or the effect of both.
Palavras-chave : self-limited epilepsies; atypical evolution; children; Panayiotopoulos syndrome.