Resumo

USTARIZ-GARCIA, Catalino R. Mastocytosis. Rev Cubana Hematol Inmunol Hemoter [online]. 2011, vol.27, n.2, pp. 196-211. ISSN 1561-2996.

Mastocytoses are included among the group of "rare diseases" due to their low frequency. They are characterized by the growth and accumulation of mastocytes on the skin and other organs for no known reason. Clinical manifestations are due to infiltration by mastocytes and the release of chemical mediators. The diagnosis is clinical and based on histopathological findings from biopsies of the skin and other organs affected, such as the bone marrow. On the skin, the illness is manifested as urticaria pigmentosa. Several classifications have been made, but none has been universally accepted. Treatment is symptomatic and does not change the course of the illness. Most patients present symptoms related to mastocyte mediator release, and prevention of its effects on tissues is crucial to the treatment.

Palavras-chave : Mastocytosis; mastocytes.

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