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Revista Cubana de Hematología, Inmunología y Hemoterapia
versão impressa ISSN 0864-0289
Resumo
GUTIERREZ-DIAZ, Adys et al. Splenectomy in sickle cell disease . Rev Cubana Hematol Inmunol Hemoter [online]. 2012, vol.28, n.3, pp. 235-245. ISSN 0864-0289.
Splenic sequestration crisis is one of the most frequent and serious manifestations of sickle cell disease in young children. The standard treatment is total splenectomy, which has the risk of fulminant sepsis with high mortality. Other complications of total splenectomy are the increased incidence of some of the manifestations of the disease, and since a few years ago it is associated with predisposition to vascular events. At the Institute of Hematology and Immunology partial splenectomy is performed since 1986 with excellent results, as it eliminates almost completely the recurrence of acute splenic sequestration without increasing the risk of infections. It has been demonstrated that the splenic remainder retains its function and no risk of vascular complications has been reported.
Palavras-chave : sickle cell disease; splenic sequestration crisis; splenectomy; venous thrombosis; pulmonary hypertension.