Resumo

POUYMIRO PUBILLONES, Pedro Omar; POUYMIRO BROOKS, Yalili  e  POUYMIRO BROOKS, Iarmila. Syndrome of antiphospholipid antibodies. MEDISAN [online]. 2012, vol.16, n.3, pp. 429-444. ISSN 1029-3019.

The antiphospholipid syndrome is an acquired multisystemic disorder and an important cause of venous or arterial thrombosis, as well as of morbidity in pregnancy. It can be primary or secondary, the last one mainly in patients with systemic lupus erythematosus, infections and consumption of some drugs. Certain elements on its clinical manifestations and the updated classification criteria for the diagnosis are exposed. The treatment is based on antithrombotic prevention measures and control of the associated risk factors; but many clinical and laboratory aspects concerning this hypercoagulability due to the presence of antibodies against phospholipids, are still under discussion and research.

Palavras-chave : antiphospholipid syndrome; venous thrombosis; arterial thrombosis; pregnancy morbidity; hypercoagulability; antithrombotic prevention.

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