Resumo

GUERRA BATISTA, Vivian Susana et al. Results of the Program of Early Detection of the Anemia for Sickle Cell in Mayarí during 2002 - 2012. ccm [online]. 2015, vol.19, n.4, pp. 605-614. ISSN 1560-4381.

Introduction: sickle cell anemia and hemoglobin SC disease are genetic diseases with autosomal recessive inheritance, they have no specific treatment. Objective: to characterize pregnant women with different types of hemoglobin electrophoresis during the period 2002 - 2012 in Mayarí Municipality, Holguin province. Method: a retrospective study was conducted, the percentage of hemoglobin electrophoresis (EF Hb) was determined according to types of pregnancies according to age, frequency of couples studied, percentage of couples diagnosed as high risk resulting from molecular studies and outcome of pregnancies with sick fetuses. Incidence of hemoglobinopathies SS and SC was calculated Results: five per cent of pregnant women had altered hemoglobins. 94.7% of the sexual partners of these pregnant women were studied. Molecular study to 85.7% of high-risk partners was performed and 88.9% of pregnant women with sick fetuses (Hb SS o Hb SC) decided to interrupt the pregnancy. The incidence rate of Hb SS or SC was 8.3 per 10 000 live births in Mayari municipality. Conclusions: the high incidence of Hb SS and Hb SC in the municipality of Mayarí pregnant during 2002-2012 supports the importance of the program for early diagnosis of sickle cell anemia.

Palavras-chave : hemoglobinopathies; sickle cell anemia; hemoglobin SC; congenital genetic diseases; inheritance pattern; pregnancy disease.

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