Resumo

RODRIGUEZ GRANA, Tania et al. Oxidative Stress: Genetics, Diet and Development of Diseases. ccm [online]. 2015, vol.19, n.4, pp. 690-705. ISSN 1560-4381.

The free radicals and the oxidative stress are involved in the pathogenesis of diverse diseases. None of the called biomarkers of the oxidative stress achieve in an isolated way a precise and definitive valuation of this disease. The recommendation of a healthy lifestyle with regular exercise and a diet based on rich products in antioxidant seems effective to prolong the survival and to reduce certain diseases. There are contradictory findings in the literature regarding the antioxidant treatments. Further studies are necessary to define the diseases, the timing and the type of the intervention as well as the patient's profile, the antioxidant treatments and their appropriate doses for a successful result. In this revision, the relationship between oxidative stress with aging, cardiovascular disease and neurodegenerative disease and antioxidative therapy was explained.

Palavras-chave : antioxidant; free radical; biomarkers; oxidative stress.

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