Resumo

FUNDORA HERNANDEZ, Hermes et al. Immunoepidemiology of bronchial asthma. Rev Cubana Hig Epidemiol [online]. 2011, vol.49, n.3, pp. 459-469. ISSN 1561-3003.

The bronchial asthma is a chronic inflammatory disease of airways. In its hereditary character are involved some genes and is influenced by many environmental factors. The objective of present review paper is to define a group of immunological factors involving in immunologic pathogenesis of this entity. The results of recent researches are emphasized which support the theory of the potentially protector effect of the infections during the early stages of life on the development of atopy later at childhood, and in other suggesting that there is a causal relation among the recurrent infections of upper airways and the development of airways hyperactivity and respiratory allergies in children. Also it approach on some immunoepidemiological researches carried out in different latitudes formulating immune response patterns found in asthmatic patients and its relation to the different disease phenotypes.

Palavras-chave : Bronchial asthma; atopy; cytokine; immunoepidemiology; immune system.

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