Resumo

ARREDONDO-RUBIDO, Alfredo Enrique  e  ARREDONDO-BRUCE, Alfredo Enrique. New advances in heart failure therapy. Rev.Med.Electrón. [online]. 2023, vol.45, n.6, pp. 1011-1020.  Epub 31-Dez-2023. ISSN 1684-1824.

Heart diseases are a topic frequently treated in medical researches, due to their wide repercussion on the functioning of the human body; therefore, the study of the treatment of these organ affections is highlighted, being an important task to maintain and enhance knowledge about therapeutic advances in diseases related to it. This work is carried out with the aim of describing the advances in heart failure therapy. A review of the scientific publications of the last two years was performed. Although there are differences regarding the proposed therapy for heart failure, the American and European Associations of cardiology firmly establish the quadruple therapy (with angiotensin receptor inhibitors neprilysin, ß-blockers; mineralocorticoids antagonist receptors and glucose/sodium cotransporters-2 inhibitors-targeted at heart failure with reduced ejection fraction-, the recommendation of isosorbide dinitrate/hydralazine for black patients, and the use of implantable cardioversion in the prevention of the sudden death. It is concluded that the harmonization of these guidelines, in both continents, provides a unique treatment for heart failure, although it needs additional study in patients with normal left ventricular ejection fraction.

Palavras-chave : heart failure; neprilysin; isosorbide dinitrate.

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