Resumo

LORES GUEVARA, Manuel Arsenio et al. NMR of Sickle Cell Disease. EAC [online]. 2012, vol.33, n.2, pp. 29-33. ISSN 1815-5928.

Magnetic Resonance applications to the study of Sickle Cell Disease are analyzed using classical procedures and Unilateral Magnetic Resonance. Hemoglobin and whole blood samples were obtained from healthy individual and patients with Sickle Cell Anemia to be used as samples. Classical pulse sequence as spin echo and inversion recovery were used in the experimental studies, the STEPR method was used for EPR spectrometric determinations. The results show the possibility of NMR methods to follow the molecular process causing the disease and allow us to present quantitative procedures to estimate the clinical state of the patients and the results of clinical options. We present the Unilateral Magnetic Resonance as a new method to study Sickle Cell disease considering its portability and new possibilities as new image method.

Palavras-chave : unilateral; magnetic; resonance; sickle; cell; disease.

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