Resumo

MARTINEZ BRITO, Dayamín et al. Human chorionic gonadotropin in doping and its control. Strategy of the Havana Anti-doping Laboratory. Anales de la ACC [online]. 2023, vol.13, n.2  Epub 08-Mar-2024. ISSN 2304-0106.

Human chorionic gonadotropin (hCG) has been included in the List of Prohibited Substances for athletes since 1987, due to its ability to increase and stabilize the endogenous production of testosterone. The aims of this paper were to describe the justification for the use of the hormone for doping purposes, relate the main hormone detection tests with the standards established in the field of sports, and describe the strategy of the Havana Anti-Doping Laboratory (LAH), in the environment of current regulations.

The LAH analysis strategy is based on a prescreening assay using a national production technology such as the Ultra-Micro Analytical System (SUMA), for the detection of the total fraction of the hormone. The quantification of the intact fraction is carried out by means of an electro chemiluminescent assay with the use of the Elecsys Cobas e411 analyzer from the German firm Roche.

Palavras-chave : human chorionic gonadotropin; immunoassay; sports; SUMA.

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