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Revista Cubana de Farmacia
versão On-line ISSN 1561-2988
Resumo
MORALES LACARRERE, Iván G; FERNANDEZ SERRET, Alfredo J; GARCIA SIMON, Gastón e ALONSO JIMENEZ, Esther. Nueva tecnología para la producción de Jarabe de Salbutamol. Rev Cubana Farm [online]. 2001, vol.35, n.1, pp. 7-12. ISSN 1561-2988.
A new technology for the production of salbutamol syrup is presented aimed at eliminating the problems of chemical and physical stability of the previous formulation, which had a useful life of less than 6 months. It was possible to obtain a new formulation that met all the quality specifications required for this drug. It was proved that its useful life increased up to 2 years stored at room temperature in its original bottle.
Palavras-chave : DRUG STABILITY; TECHNOLOGY, PHARMACEUTICAL; CHEMISTRY, PHARMACEUTICAL [methods]; DRUG COMPOUNDING [methods]; ASTHMA [drug therapy]; ALBUTEROL [pharmacology]; ALBUTEROL [pharmacokinetics].