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Revista Cubana de Pediatría
versão On-line ISSN 1561-3119
Resumo
POZO ALONSO, Albia J.; POZO LAUZAN, Desiderio e POZO ALONSO, Desi. Síndrome de West: etiología, fisiopatología, aspectos clínicos y pronósticos. Rev Cubana Pediatr [online]. 2002, vol.74, n.2, pp. 151-161. ISSN 1561-3119.
West syndrome is an age-dependent epileptic encephalopathy characterized by electoclinical triad of epileptic spasms, retardation of psychomotor development and electroencephalographic pattern of hipsarrythmia, although one of these elements may not be present. The majority of patients develop this syndrome in the first year of life. From the etiological viewpoint, Western syndrome is idiopathic, cryptogenic and symptomatic. The prenatal causes are the most frequent ones. Various hypotheses have been presented to explain the origin of West syndrome. Epileptic spasms are the characteristic crises that can be in flexion, extension or combined. A review is made on important aspects of etiology, physiopathology, clinical manifestations, differential diagnosis and prognosis of West syndrome.
Palavras-chave : SPASMS, INFANTILE [diagnosis]; SPASMS, INFANTILE [etiology]; SPASMS, INFANTILE [physiopathology]; PROGNOSIS; EPILEPSY; INFANT.