Resumo

RODRIGUEZ CARDENAS, Antonio et al. Use of Misoprotol to induce abortion up to 9 weeks. Rev Cubana Obstet Ginecol [online]. 2008, vol.34, n.3, pp. 0-0. ISSN 1561-3062.

OBJECTIVE: to evaluate the efficiency and safety of self-vaginal administration of 800 µg of Misoprostol, one dose every 8 hours up to a maximum of 3 doses and 2 cycles in a period of 48 hours to induce abortion in a group of 214 patients with less than 63 days of gestation. METHODS: a clinical, descriptive and prospective study was conducted. The universe consisted of all the patients that were seen at the familiy planning department of "América Arias" Gynecoobstetric University Hospital from January 15 2006 to November 21 2006. RESULTS: the method was considered efficient when the complete abortion was attained with no surgical procedures, which occurred in 193 patients (90,2 E %). The highest effectiveness was obtained with the first cycle of treatment in 185 cases (86.4 %). There were 21 fails (9.8 %), 15 of them due to failure of the methods after the administration of the third dose of the second cycle, 4 for medical decision and 2 because of patient's decision. The most significant secondary effects were chills (55.1 %), nausea (32.7 %), pelvic pain (73.8 %) and uterine bleeding above the menstrual bleeding (63.1 %). CONCLUSIONS: the results suggest that the administration of a dose of 800 µg of Misoprostol every 8 hours by vaginal route is an adequate method to interrupt pregnancy between the 6 and 9 weeks of gestation.

Palavras-chave : Misoprostol; therapeutic use; induced abortion; methods.

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