Resumo

RODRIGUEZ RODRIGUEZ, Yoel; BEATO CANFUX, Abraham  e  GARCIA SANCHEZ, Maura. Link between the oxidative stress and burn disease. Rev Cub Med Mil [online]. 2012, vol.41, n.1, pp. 105-115. ISSN 0138-6557.

A bibliographic review was carried out on the oxidative stress taking into account the normal physiology of this metabolic mechanism, the causes of its alteration and the damaged produced, when the defense organic system are unbalanced to evidence the link between the oxidative damage to cells and the physiology and pathology of the injuries produced by major burns, from the analysis of the printed bibliographic national and international sources and in digital format on this subject. The significance to design more effective strategies is emphasized that take into account the magnitude of the damage produced by the oxidative stress in the treatment of burnt patients to modulate the oxidative damage to cells. We conclude that in the medical practice it is not possible to avoid to patients the new situation of redox state. The healthcare efforts must to be directed once again to help to organism in restoration of redox balance by means of an appropriate and early recovery with practices of active surgical tactics minimizing the external damages, supply appropriately the nutrients and to respect the politic of use of systemic antibiotics, by means of the use of parental antioxidants to reduce the hospital stay with the support of psychologists and physiatrist trained in the therapy used.

Palavras-chave : oxidative stress; free radicals; oxidative damage; major burns; diseases due to burns.

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