Resumo

GARCIA VEGA, Edel; FERNANDEZ ANDREU, Carlos M  e  RIVERO FIGUEROA, Dianelys. Epidemiological, clinical, microbiological and therapeutic aspects of histoplasmosis. Rev Cub Med Mil [online]. 2013, vol.42, n.1, pp. 94-105. ISSN 0138-6557.

Histoplasma capsulatum is considered a dimorphic fungus. It is an endemic mycosis presenting opportunistic behavior. Its transmission is mainly by respiratory inhalation of naturally occurring conidia. The clinical conditions may vary from asymptomatic infections to severe disease spread, especially in AIDS patients, transplant or with haematological malignancies patients. The diagnosis of the fungus is obtained from body fluids or tissues, the culture of biological materials and serology. The database used in this work was selected from SciELO, HINARI, PubMed, Medline databases and various texts and articles donated by specialists, which were very useful material for this review. The papers found showed useful and valuable information of histoplasmosis, which is a breathing entity considered the most common fungal infection in immuno-competent patients and the third cause of death in AIDS patients. The objective of this review is to present an update on key clinical, epidemiological, microbiological and therapeutic systemic fungal infection, which are most common in Cuba and America.

Palavras-chave : histoplasmosis; Histoplasma capsulatum; systemic mycoses.

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