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Revista Cubana de Medicina Militar
versão On-line ISSN 1561-3046
Resumo
HERRERA CARTAYA, Carlos Enrique et al. Age as a variable associated with severity in patients with COVID-19. Rev Cub Med Mil [online]. 2022, vol.51, n.1 Epub 01-Mar-2022. ISSN 1561-3046.
Introduction:
COVID-19, rocked the world in December 2019. Since its inception, it has been observed that older patients are prone to develop severe forms of the disease.
Objective:
To determine the role of age as a variable associated with severity in COVID-19 patients.
Methods:
A retrospective cohort analytical study was conducted in 150 patients diagnosed with COVID-19, during March to June 2020. The severity was analyzed according to age groups, and a simple binary logistic regression model was used. Clinical and laboratory variables at hospital admission were summarized for the comparison of two age groups from the optimal cut-off point for age using the ROC curve. The free software R version 4.0.2 (22-06-2020) was used for processing.
Results:
The age of the patients had a wide range, with disease severity predominating in the older age groups. The optimal cut-off point calculated was 71.5. Was observed that from 70 years of age onwards patients had greater comorbidity and altered laboratory tests. Likewise, a greater number of symptoms, hospital stay, and number of deaths.
Conclusions:
Age is a risk factor associated with severity in patients with COVID-19, which increases significantly after 70 years of age, where a series of factors coexist which, together with advanced age, play an important role in the prognosis.
Palavras-chave : COVID-19; age; risk; prognosis; comorbidity.