Resumo

GARCIA ROSASCO, Marcela; LIPPI, Samanta  e  VALVERDE, Juana. Frequency of blood groups A₁, A₂, A_int,B and O in normal subjects. Rev Cubana Hematol Inmunol Hemoter [online]. 2001, vol.17, n.3, pp. 171-174. ISSN 1561-2996.

Blood cells that share characteristics with A₁ and A₂ are defined as A-intermediates. There are qualitative and quantitative differences in epitope A. Blood cells A₁ are binded by Dolichus biflorus lectin(ant1-A₁), blood cells A₂ are binded by Ulex europareus lectin (anti-H) whereas A_int are indistinctively binded by both lectins in an unexpected way. A_int subjects were looked for among normal healthy individuals according to their reaction to the aforementioned lectins. Our results agree with previous remarks on the marked heterogenecity of blood cells A_int . One-thousand three hundred one samples were studied resulting in 703 from O group (54,04%); 468 from A group (35,97%); 106 from B group (8,15%); 18 from A₁B (1,38%) and 6 from A₂B (0,46%). The samples A were subdivided into 346 A₁(73,93%), 82 A₂ (17,52%) and 40 A_int (8,55%). The detection of weak subgroups within the A group has a great importance for forensic practice and the study of population's dynamics. The study of A_int variant is relevant in Population Immunogenetics because of its contribution to the knowledge of crossbreeding with Black populations

Palavras-chave : BLOOD GROUPS [immunology]; IMMUNOGENETICS [methods]; GENETIC MARKERS [immunology]; ABO BLOOD GROUP SYSTEM [immunology]; POPULATION DYNAMICS.

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