Resumo

ALFONSO-SIMON, Amel; FEISTO-CASTEX, Teresita; LLOPIZ-CASANOVA, Linnet  e  HERNANDEZ-RAMIREZ, Porfirio. Quality of life in patients with chronic lower limb ischemia treated with adult stem cells. Rev Cubana Hematol Inmunol Hemoter [online]. 2012, vol.28, n.4, pp. 398-403. ISSN 0864-0289.

An assessment of the quality of life in 45 patients older than 60 years with chronic arterial ischemia of the lower limbs was conducted. Out of them, 34 had severe ischemia, and 11 had ischemic diabetic foot, as well as severe injuries. All had been implanted mononuclear cells in the affected lower limb, which derived from the bone marrow, and mobilized to the peripheral blood with granulocyte colony stimulating factor. For assessing quality of life, SF-36 questionnaire was selected, which focuses its content on two areas: functional status and emotional well being. All cases showed poor quality of life before implantation. Improvement was evident on the sixth month after cell therapy. Cases with a year of evolution had achieved good quality of life. Most of the patients, who had successful outcomes, could join social activities and employment, which was previously not possible.

Palavras-chave : quality of life; lower limb ischemia; adult stem cells.

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