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Revista Cubana de Hematología, Inmunología y Hemoterapia

versão On-line ISSN 1561-2996

Resumo

PEREZ PEREZ, Marisol et al. Immunogenetic characterization of Cuban cadaveric donors in 2019. Rev Cubana Hematol Inmunol Hemoter [online]. 2022, vol.38, n.2  Epub 01-Jun-2022. ISSN 1561-2996.

Introduction:

Transplantation is the most favorable therapeutic option for people with chronic renal failure. The donor can be a cadaveric or living donor, related or not. Transplant outcomes are related to various immunological and non-immunological factors.

Objective:

To characterize Cuban cadaveric donors for renal transplantation

Materials and methods:

A cross-sectional and descriptive study of cadaveric donors was carried out during the year 2019. The region of origin, sex, skin color and age ranges of the donors were analyzed, as well as ABO and Rhesus Rh blood groups; serology for HIV, Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV), and toxic habits.

Results:

A total of 95 cadaveric donors were studied, 62 from the West and 33 from the Center of the country. 63.2% were male and 36.8% female due to the most frequent age group being 40-60 years and the mean age of 49.45 years. 58.95% of the patients were of blood group O, 30.53% group A and groups B and AB had 5.26% prevalence; and only 8 were Rh negative. All had negative serology for HIV, HBV and HCV. The most frequent associated diseases were arterial hypertension and diabetes mellitus.

Conclusions:

The cadaveric donors during the year 2019 showed characteristics similar to those reported by other studies. The increase in the age of the donors affects the appearance of associated diseases and this could affect the result of the transplant.

Palavras-chave : cadaveric donor; chronic renal failure; immunogenetics; kidney transplant.

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