Resumo

CABRERA ROJO, Iliana. Cardioprotección: un triunfo de la biomedicina del siglo XX. Rev Cubana Invest Bioméd [online]. 1999, vol.18, n.2, pp. 146-150. ISSN 1561-3011.

Cardioprotection means prevention of vascular coronary damage and of cardiac cyocites, which is achieved by internal mechanism of the body and through various pharmaceuticals. This involves vasodilation, inhibition of oxygen free radical generation, incresase of tissue ATP and reduction of microvascular damage. The mechanisms of endogenous, metabolic and phatmacological cardioprotection are reviewed, and also the function of betablokers, calcium channel blockers, angiotensin-converting enzime inhibitors, and the use of trimetazidine as anti-cell ischemia are underlined.

Palavras-chave : MIOCARDIAL ISCHEMIA [preventive control]; INSULIN [pharmacology]; GLUCOSE [pharmacology]; CALCIUM CHANNEL BLOCKERS [pharmacology]; ADRENERGIC BETA-ANTAGONISTS [pharmacology]; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS [pharmacology]; TRIMETAZIDINE [pharmacology].

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