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Revista Cubana de Investigaciones Biomédicas

versão On-line ISSN 1561-3011

Resumo

DIAZ BATISTA, Arquímides; GARCIA MESA, Milagros; PINA MANRESA, Carmen  e  MENENDEZ CEPERO, Silvia. Efecto del ozono sobre la activación plaquetaria en pacientes diabéticos tratados con ozonoterapia: informe preliminar. Rev Cubana Invest Bioméd [online]. 2001, vol.20, n.1, pp. 45-47. ISSN 1561-3011.

Whether there is inhibition of platelet aggregation or not after treatment (10-20 days) was tested in vivo in those patients diagnosed with an ischemic or neuroinfectious diabetic foot and treated with 200 mL of ozone. Platelet aggregation found at the onset of treatment showed a mean of 28,3 % and a range from 60 to 6,25 % whereas after completing the therapy, it was reduced to a mean of 17,5 % and a range from 16,25 to 18,75. The aim of this preliminary study was to prove whether inhibition of platelet aggregation occurs after the ozone therapy, the same as was observed by other authors in vitro. A reduction of the platelet aggregation percentage was noticed at the end of the ozone therapy as compared with the initial values

Palavras-chave : OZONE [therapeutic use]; PLATELET AGGREGATION [drug effects]; DIABETIC FOOT [drug therapy]; DIABETES MELLITUS [complications].

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