Objective:

To describe the differences in burnout syndrome (BS) before and during the COVID-19 pandemic among health professionals, according to prevalence, levels, sociodemographic, occupational, risk, and protective factors.

Methods:

A comparative descriptive study was conducted, with two samples of similar characteristics from public hospitals in Peru. The sample was 177 for 2019 and 167 for 2021. The instrument used was the Maslach Burnout Inventory.

Results:

It was found that there is a higher prevalence of BS and lower personal fulfillment (PF) during the pandemic. For BS, female sex is a risk factor during the pandemic. For emotional exhaustion (EE), the female gender is a risk factor before and during the pandemic. For depersonalization (DP), being 39 years of age or older is a protective factor before the pandemic.

Conclusions:

There are significant differences in the scores of BS, EE, and PF; no significant differences for DP were found in both periods.

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