Introduction:

Dengue has become one of the largest epidemiological, social, and economic impacts for global public health.

Objective:

To determine the seroprevalence of dengue in five municipalities of Valle del Cauca with hyperendemic and mesoendemic transmission of the disease.

Methods:

Prevalence study through multistage probability sampling by clusters. 822 people were assessed.

Results:

Seroprevalence of dengue was of 91.36 %, it was obtained from the implementation of the enzyme-linked immunosorbent´s trial test for indirect dengue IgG. When applying the capture test IgM for dengue, seroprevalence was of 21.41 %. The joint seropositivity of IgM and IgG antibodies was 20.3 %.

Conclusions:

The high seroprevalence of dengue in Valle del Cauca shows the impact of this disease in the life history of the residents. Dengue re-emergence impacts negatively on those who have a background of having suffered from the disease which caused a development of its most severe variant that can be avoided with the administration of a quadrivalent vaccine against dengue.

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