Resumo

HERRERA LORENZO, Orestes; INFANTE FERRER, José  e  CASARES ALBERNAS, Fermín. Myasthenia Gravis: diagnosis and treatment. AMC [online]. 2009, vol.13, n.5, pp. 0-0. ISSN 1025-0255.

In this work we intend to update the topic of Myasthenia Gravis emphasizing in diagnosis and management as much in the community as in the intensive care units. Main diagnostic methods accepted internationally are commented and in equal form the therapeutic measures approved by the evidence, it is also commented some of the main challenges and controversies related with diagnosis and treatment. Myasthenia Gravis is an autoimmune, frequent and controllable disease, many of its symptoms and signs may become confused with several neurological affections, that is why its precocious diagnosis is of supreme importance for the realization of the thymectomy in the briefest term, mainly in those patients smaller than sixty years and with life expectancy superior to ten years. In absence of a more specific biological marker for diagnosis, we recommend the use of the clinical criteria mentioned, although it is hope that in the next years a true revolution in the physiology comprehension of the neuromuscular junction and of the myasthenic syndrome particularly.

Palavras-chave : neuromuscular junction; myasthenia gravis; antireceptor antibodies; acetylcholine; thymectomy.

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