Resumo

ALVAREZ, Nadine et al. Obtainment and partial characterization of a lipidic fragment of the outer membrane of Mycobacterium smegmatis. Vaccimonitor [online]. 2009, vol.18, n.1, pp. 15-19. ISSN 1025-0298.

Currently, lipid antigens of mycobacteria are attractive targets for the development of new tuberculosis vaccinal formulations. A lipid extract of Mycobacterium smegmatis cell wall was characterized using a Thin Layer Chromatography and Dot blot with human gammaglobulin. Mainly we identified the presence of phospholipids and micolic acids in the lipid extract showing a high recognition by human gammaglobulin. These results indicate the relevance of continuing immunoprotection studies with mycobacterial lipid antigens.

Palavras-chave : Mycobacterium smegmatis; Tuberculosis; Mycobacterium smegmatis,; lipids.

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