Resumo

LLANIO VILLATE, Mirta et al. Plectranthus amboinicus (Lour.) Spreng. (orégano francés): efecto antimuscarínico y potenciación de la adrenalina. Rev Cubana Plant Med [online]. 1999, vol.4, n.1, pp. 29-32. ISSN 1028-4796.

We investigate the acqueous extract effect from P. amboinicus on isolated ileum of gunea pigs and deferent ductus in rats. Acqueous extract produced a competitive type of muscarinic cholinergic antagonism on guinea pigs isolated ileum, and deferent ductus in rats; and an increase of exogenous adrenaline was observed. Moreover, results obtained in electrically-stimulated deferent ductus in rats, suggest that acqueous extract of the plant, to inhibit intraneuronal receptation of catecholamines. Anti-muscarinic and adrenegir effects may contribute to antiepileptic action and at once, represent a potential antidepressant activity.

Palavras-chave : PLANT EXTRACT [pharmacology]; PLANTS MEDICINAL; ILEUM [drug effects]; VAS DEFERENS [drug efects]; GUINEA PIGS; RATS.

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