Resumo

JIMENEZ NIEVES, Lesly et al. Toxicidad aguda oral del Xanthium strumarium L. (guizazo de caballo). Rev Cubana Plant Med [online]. 1999, vol.4, n.1, pp. 40-43. ISSN 1028-4796.

An experimental study was carried out to assess potential toxic effect of fluid extract in 65 % hydroalcoholic solution of Xanthium strumarium L. In this study authors used Acute Toxicity Classes Method (ATC) from preestablished dose of 25.200 and 200 mg/kg of body weight. Animals used were Wistar rats, with a body weight between 150 and 200 g. Results confirmed and supported safety of the plant because of there weren´t clinical signs evidencing toxicity and deaths with a dose of 2 000 mg/kg; which is limit dose, according to standard used.

Palavras-chave : PLANTS MEDICINAL [toxicity]; PLANT EXTRACTS [toxicity]; RATS WISTAR.

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