Resumo

NOCHE GONZALEZ, Gisela; HERRERA MARTINEZ, Manuela; NOA MACHADO, María Dolores  e  CASANOVA NOCHE, Patricia. Relation of the reproductive behaviour in women according to age and cytogenetic prenatal diagnosis in Placetas. Medicentro Electrónica [online]. 2015, vol.19, n.4, pp. 209-217. ISSN 1029-3043.

Introduction: prevalence of Down syndrome can be a result of the reproductive behaviour due to the maternal age at delivery or due to the cytogenetic prenatal diagnosis. Objective: to characterize the relation of the reproductive behaviour in women according to age and cytogenetic prenatal diagnosis in Placetas municipality. Methods: a descriptive study of transversal type was carried out in order to evaluate maternal age in 1440 births and the Down syndromes occurred, regardless of the destiny of the product, in Placetas municipality from January, 2011 to June, 2013; there were also evaluated the parameters of effectiveness of actions of the Community Genetics in cytogenetic prenatal diagnosis for maternal age groups (real and global range, proportion of positivity of the study and prevention). At the same time, results of cytogenetic prenatal and postnatal studies were described, and the age- adjusted prevalence of chromosomal abnormalities and Down syndromes was established, as well as, their relationship with maternal age. Results: natality over 35 years was of 10.8 % in this period in Placetas, and the age- adjusted prevalence of Down syndrome was of 4,17 % for each thousand born alive in all ages. Proportion of positivity of the study was of 5,95 % at advanced ages, and the prevention of the 100 % of women at advanced maternal age was achieved. Conclusions: there was a satisfactory range with the prenatal cytogenetic diagnosis in women who had an advanced maternal age and the prevention of the 100 % of Down syndrome was also achieved in this group of women

Palavras-chave : prenatal diagnosis; cytogenetic analysis; maternal age; down syndrome.

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