Resumo

NAVARRO DESPAIGNE, Daysi A.. Interrelation between thyroid hormones and growth: clinical importance. Rev Cubana Endocrinol [online]. 2005, vol.16, n.3, pp. 0-0. ISSN 1561-2953.

In the clinical practice of pediatric endocrinology, growth disorders is the most frequent reason to go to the doctor´s , being thyroid hypofunction the most common cause of this problem. For this reason, we intended to review theoretical aspects of thyroid function that could explain the mechanism by which thyroid hormones intervene in the development of growth cartilage and of the central nervous system. The regulating thyroid hormone mechanism along with the effect of growth factors on both intrauterine and postnatal life stages was briefly examined. A hypothesis of how the interrelation between thyroid hormones (growth factors) occurs was presented. Finally, reference was made on the clinical impact of thyroid hormone deficit in childhood.

Palavras-chave : Congenital hypothyroidism; lineal growth; growth and development; thyroid hormones; growth factors.