Resumo

CALDERIN BOUZA, Raúl Orlando  e  ORLANDI GONZALEZ, Neraldo. Metabolic syndrome vs insulin resistance syndrome. Different terms, classifications and approaches: Does it exist or not?. Rev Cubana Endocrinol [online]. 2006, vol.17, n.3, pp. 0-0. ISSN 1561-2953.

Eventhough Gerald M Reavaen described in 1988 the X syndrome, it has received multiple names in the course of time. The metabolic syndrome (MS) and the insulin resistance syndrome (IRS) are the most accepted. The first refers to a series of risk factors of lipids and nonlipids of metabolic origin; whereas the second, the most complete and adequate, describes a group of abnormalities and related clinical results that appear more commonly in individuals with insulin resistance (IR) and compensatory hyperinsulinemia associated with a chronic inflammatory state. Some authors have questioned its existence, but the evidences speak for themselves. The objective of this review is to make an analysis of the different approaches and classifications for its diagnosis, to recommend the classification of the NCEP-ATP III, due to its feasability, application in the clinical practice and in the epidemiological studies, and to insist on the view that the IRS results from IR, as well as from a chronic inflammatory state associated with some cardiovascular risk factors (CVRF), and from related clinical situations that confer it an elevated risk for developing type 2 diabetes mellitus (type 2 DM) and cardiovascular disease (CVD).

Palavras-chave : insulin resistance syndrome (IRS); insulin resistance (IR); hyperinsulinemia; metabolic syndrome (MS); type 2 diabetes mellitus; dyslipidemia; arterial hypertension (AHT).