Resumo

SABIDO-TOLEDO, Lisbeth. Severe adverse skin reactions in the childhood. Rev.Med.Electrón. [online]. 2021, vol.43, n.6, pp. 1660-1673.  Epub 31-Dez-2021. ISSN 1684-1824.

Skin reactions to drugs are increasingly common at pediatric ages, with a high impact on children's health. They can appear in very dissimilar forms, from a transient rash to serious pictures with potentially fatal multisystem involvement. This review focuses on severe pharmacodermies in the childhood, with the aim of promoting medical staff knowledge to facilitate their timely diagnosis and treatment. A search was led in the Infomed Virtual Health Library and in Google: 28 scientific papers were reviewed without limitation of year and country, 24 of them belong to the last five years and from these 17 to the last three. Mastery of the elements for early diagnosis and therapeutic options are indispensable to choose the appropriate behavior against these serious skin reactions and to decrease morbidity and mortality due to these conditions.

Palavras-chave : skin reactions to drugs; pharmacodermies; Stevens-Johnson syndrome; toxic epidermal necrolysis; DRESS syndrome; children.

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