Resumo

ARMAS CASTRO, Julio; CARRASCO GARCIA, Mayra Rosa  e  ANGEL VALDES, Sussette. Roles in the progression from mild cognitive decline, to Alzheimer’s disease. Rev haban cienc méd [online]. 2008, vol.7, n.4, pp. 0-0. ISSN 1729-519X.

Mild cognitive decline and dementia are both important health problems in the 21ist century . Given it’s connection with age, we have stated how, in the last decade a continuum increase in it’s incidence and prevalence is related with the progressive increase time of life. Having in consideration the studies of progression made up to date and the cohorts of following of mild cognitive decline, we can point out some markers of evolution, given: advanced age, the presence of at least one APOE 4 allele in genetic screening, diminished hippocampus area, low punctuations in psychometric tests, a major cardiovascular compromise and family background of first blood line relatives with dementia, among others. We had the purpose to approach the subject of the predictor factors with the main objective to offer updated information about the performed studies in connection with the topic.

Palavras-chave : Mild cognitive decline; Senile dementia; Alzheimers disease; APOE 4; Neuropsychological tests.

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