Resumo

RODRIGUEZ SUAREZ, Eliana et al. From limb weakness to a systemic involvement: Poems syndrome case two report and review of the literature. Rev Cuba Reumatol [online]. 2022, vol.24, n.4  Epub 01-Dez-2022. ISSN 1817-5996.

POEMS syndrome is a rare and infrequent paraneoplastic syndrome, which occurs mainly in the sixth decade of life, characterized by multisystem involvement with a predominance of demyelinating neuropathy, which encompasses diverse and heterogeneous clinical manifestations and whose diagnosis requires a high index of suspicion. We present two cases of patients who consulted due to unusual symptoms and whose loss of strength led to an approach due to multisystem involvement that concluded with the diagnosis of this disease.

Palavras-chave : polyneuropathy; organomegaly; endocrinopathy; monoclonal gammopathy; POEMS syndrome.

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