Background:

gonarthrosis is an entity with a slow and progressive course that ends with joint destruction. The use of alternative methods, based on regenerative medicine such as the intraosseous application of platelet-rich plasma, is a therapeutic modality that relieves pain and improves the functional capacity of patients with primary gonarthrosis.

Aim:

to update knowledge regarding the use of platelet-rich plasma intraosseously.

Methods:

the search and analysis of the information was carried out in a period of four months (January 1, 2022 to April 30, 2022) and the following words were used: platelet-rich plasma and knee osteoarthritis, intraosseous injection of platelet-rich plasma. Based on the information obtained, a bibliographic review of a total of 203 articles published in the PubMed, Hinari, SciELO and Medline databases was carried out using the search engine and reference manager EndNote.

Development:

the main indications are mentioned, as well as the steps to carry out the procedure. The technique to be used is described as the frequency of its application. Reference is made to the main differences between the intraarticular and intraosseous routes. Outcome: the application of PRP in patients with knee osteoarthritis constitutes a variety of useful treatment. The intraosseous administration offers advantages in relation to the improvement of symptoms and signs of this disease.

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