Resumo

WISNIAK, Jaime. JEAN-BAPTISTE PAUL CAZENEUVE Physician, chemist, and politician. Rev. CENIC Cienc. Biol [online]. 2022, vol.53, n.1, pp. 56-68.  Epub 07-Mar-2022. ISSN 2221-2450.

Jean-Baptiste Paul Cazeneuve (1852-1934) was a successful a French physician, chemist, and politician that carried basic research of physiological subjects and vegetable principles. He demonstrated that the Guilliermond process (based on the direct action of lime on the vegetable matter) reduced substantially the time required to extract and separate alkaloids as well as a variety of first principles. He demonstrated it by extracting alkaloids such as strychnine, solanine, quassin, cocaine, veratrine, rhœadine, and active principles like catechin. He was the first to isolate pterocarpin from red sandalwood and to show with Hugounenq that this principle was actually a mixture of two principles, homopterocarpin and pterocarpin. They also determined their chemical and physical properties, including their composition. Latour and Cazeneuve demonstrated that catechin was the astringent agent of mahogany, and Cazeneuve and Haddon determined the properties and composition of caffeinic acid. Cazeneuve studied in detail hematin, the normal coloring substance of blood, developed a fast process for separating it, and concluded that it contained iron.

Palavras-chave : alkaloids; catechin; hematin; pterocarpin; vegetable principles.

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