Meu SciELO
Serviços Personalizados
Artigo
Indicadores
- Citado por SciELO
Links relacionados
- Similares em SciELO
Compartilhar
Revista Cubana de Química
versão On-line ISSN 2224-5421
Resumo
DIP, Ariamna et al. Synthesis of prenylated chalcones potentially bioactives through consecutive reactions of Claisen's rearrangement and condensation. Rev Cub Quim [online]. 2016, vol.28, n.3, pp. 834-842. ISSN 2224-5421.
The introduction of prenyl and hydroxyl groups in the structure of chalcones could produce new structural analogs with potential biological activity. The synthesis of these compounds is an interesting way for obtaining new therapeutic agents. Using Claisen's rearrangement and condensation reactions assisted by microwaves two prenylated chalcones were obtained with moderate yields (47-52%) and a high degree of purity. The synthetized compounds were structurally characterized by nuclear resonance spectroscopy, infrared spectroscopy, high resolution mass spectrometry and elementary analysis.
Palavras-chave : prenylated chalcones; Claisen's rearrangement; Claisen's condensation.