Resumo

GARCIA CHAVIANO, Yipsi et al. Albendazol and Triclabendazol as Treatment for Fasciolosis in Sheep. Rev. prod. anim. [online]. 2016, vol.28, n.1, pp. 44-47. ISSN 2224-7920.

The aim of this study was to evaluate the activity of Albendazole (ABZ) and Triclabendazole (TBZ) in a sheep flock naturally infected with F. hepatica. The faecal egg count reduction test (HPG) was used in 12 adult sheep in a farm located in Camagüey province, Cuba. The animals were distributed into two treated groups (ABZ=G1 and TBZ=G2: critical study) and at day 0 received an oral dose of each drug. Stool samples were collected at 0, 14 and 28 days after treatment. The modified McMaster technique was used with ZnSO4 solution at 1.5 g/mL having an analytic sensitivity of 10 eggs per gram of faeces. We observed 98.17 and 79.58 % egg reduction at day 14 for G1 and G2, respectively. At day 28, G1 showed only 33.94 %, while G2 demonstrated 90.39 % of eggs reduction. G2 provided more time of F. hepatica egg reduction than G1. We may justify the high efficacy of TBZ by its exclusive action against juvenile and adult stages of F. hepatica. We also report the lack of efficacy and persistency of action of ABZ against F. hepatica being a risk in the control of the parasite and the maintenance of animal welfare.

Palavras-chave : trematode; parasite; F. hepatica; egg; resistance.

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