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Revista Cubana de Farmacia

versão On-line ISSN 1561-2988

Resumo

GONZALEZ LAVAUT, José A; ALVAREZ SOTOLONGO, Marta; PEREZ PONS, Jorge  e  DIAZ ABIN, Osmel. Análisis físico-químico de la sal sódica de la prostaciclina obtenida en Cuba. Rev Cubana Farm [online]. 1999, vol.33, n.3, pp. 171-176. ISSN 1561-2988.

The physical and chemical analysis of prostacyclin sodium salt was made by infrared spectroscopy, proton-emission and carbon-13 nuclear magnetic resonance. To corroborate the structure of the studied molecule, the product of its hydrolysis, 6-ketoprostaglandin F1a , was also studied by infrared spectroscopy, and proton-emission and carbon-13 nuclear magnetic resonance assisted by COSY techniques. The report of the elemental composition was made, too. A study of the hydrolytic transformation of prostacyclin sodium salt into 6-keto-prostaglandin was carried out by high resolution liquid chromatography, which confirmed that this is the only product obtained in such a process.

Palavras-chave : EPOPROSTENOL [chemistry].

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