Resumo

GUTIERREZ GAITEN, Yamilet Irene et al. Suspensión oral antidiarreica de Psidium guajaba, L. Rev Cubana Farm [online]. 2000, vol.34, n.1, pp. 44-49. ISSN 1561-2988.

The standarization of a raw drug from Psidium guajaba L. As well as the design and production of an oral antidiarrheal suspension from this plant after drying and sieving were carried out. It was found that all the assesed quality parameters were within the limits set the Public Health Branch Standard 308 of 1992. The physical, chemical and microbiological stability of the designed formulation was determined, with satisfactory results during 270 days of testing. Finally, a preliminary pre-clinical study was conducted, taking the pharmacological tests in rats into consideration, which resulted in the formulation having an antidiarrheal effect with doses of 3,6 and 9 mg per kg of weight under experimental conditions.

Palavras-chave : ANTIDIARRHEALS [standards]; PLANT EXTRACTS [standards]; PLANTS, MEDICINAL; DRUG STABILITY; DRUG QUALITY.

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