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Revista Cubana de Farmacia
versão On-line ISSN 1561-2988
Resumo
PEREZ SUAREZ, Liana Liz; FERNANDEZ SERRET, Alfredo e ALONSO JIMENEZ, Esther. Técnica analítica para el estudio de estabilidad del Cromoglicato de Sodio (Cápsulas para inhalación). Rev Cubana Farm [online]. 2001, vol.35, n.1, pp. 28-33. ISSN 1561-2988.
An analytical method was developed by high pressure liquid chromatography to determine the content of sodium cromoglicate in capsules. The technique developed proved to be linear, precise, accurate and specific and it was used to conduct the study of accelerated stability and that of shelf life. The chemical stability of the drug was verified for a period of 2 years.
Palavras-chave : DRUG STABILITY [methods]; CROMOLYN SODIUM [pharmacokinetics]; CHROMATOGRAPHY, HIGH PRESSURE LIQUID [methods]; DRUG QUALITY; CHEMISTRY, PHARMACEUTICAL; CAPSULES [analysis].